OneFlow

OneFlow™ enables the rapid and consistent generation of highly uniform spheroids and organoids, a critical asset for labs transitioning towards animal-free research models in line with recent FDA recommendations. The system can produce tens of thousands of spheroids in minutes, with exceptional size homogeneity—ideal for drug screening, toxicology, and tissue engineering applications.

The platform supports a wide range of encapsulation protocols, from single-cell to multi-cell droplets, co-encapsulation of multiple reagents or cell types, reagent addition and merging of droplets for complex assays. This flexibility makes it suitable for both current and future experimental needs.

OneFlow™ features an integrated camera and microscope, easy parameter control, and SMART connectivity for rapid setup and minimal training. The zero dead volume design ensures maximum sample efficiency, which is particularly important when working with precious or limited biological materials.

Its compact footprint and compatibility with biosafety cabinets makes it ideal for sterile workflows and routine use in regulated environments.​

While OneFlow™ does not include modules for optical detection or dielectrophoretic sorting, it is fully upgradable to the ModaFlow™ specification. This allows laboratories to start with a cost-effective encapsulation solution and later add advanced features as research needs evolve, avoiding redundant investments. This staged approach is especially attractive for groups whose immediate readouts can be performed externally (e.g., PCR, imaging).

OneFlow™ is a robust, adaptable platform that empowers your lab to embrace the future of microfluidics—delivering immediate value for 3D cell culture and the flexibility to grow into advanced droplet-based applications, all with a clear and cost-effective upgrade path.​